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About Us

  • We align with evolving global regulatory trends, including FDA initiatives, to support a shift toward reduced reliance on animal models.​

  • We integrate micro-/nano-fabrication technologies with stem cell biology to engineer advanced, human-relevant tissue and organoid systems.​

  • Our iPSC-derived organoid platforms enable disease modeling and drug evaluation.

Technology

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  • Self-Sustained Traveling-Wave–Based Cardiac Maturation

We employ a self-generated traveling wave mechanism that does not require external pacing devices to functionally train immature iPSC-derived cardiomyocytes, promoting electrophysiological and mechanical maturation.

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  • Dual Excitation–Contraction Recording System

We develop a dual excitation–contraction recording system that enables simultaneous measurement of electrical activity and contractile force in cardiomyocytes and engineered cardiac tissues, providing comprehensive electromechanical functional assessment.

  • Cell evaluation

We employ a combination of Raman spectroscopy, molecular biology techniques, and other advanced analytical approaches to comprehensively evaluate cellular function, physiological status, and resistance to stress or injury. By integrating AI-powered data analysis, we generate detailed and actionable cell characterization reports, providing deep insights into cell quality, functionality, and therapeutic potential.

Company Profile

Company Name

EngiTissue Design Co., Ltd.

Date of Establishment

2024.12.26

Head Office

Techno Alliance Building C, 2-8 Yamadaoka, Suita, Osaka 565-0871 Japan

Laboratory

Room 319, Photonics Center (P3), 2-1 Yamadaoka, Suita, Osaka 565-0871 Japan

Business Activities

  • Design and manufacturing of iPSC-derived  organoids

  • Development of 3D tissue platforms for disease modeling and drug screening

  • Cardiac tissue chips for cardiotoxicity and drug efficacy evaluation

  • Technical development and collaborative research support in tissue engineering

Main Clients

  • Universities and public research institutions

  • Pharmaceutical and biotechnology companies

  • Contract Research Organizations (CROs)

Capital

 JPY 100 million

Contact

Contact us

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